Scientist III, Protein Biology

Work Schedule Standard (Mon-Fri) Environmental Conditions Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.) Job Description About the company Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, with annual revenue of approximately $44 billion. Our Mission is to enable our customers to make the world healthier, cleaner, and safer. Whether our customers are accelerating life sciences research, solving analytical challenges, growing efficiency in their laboratories, improving patient health through diagnostics, or developing and manufacturing life-changing therapies, we are here to support them. Our distributed team delivers an outstanding combination of innovative technologies, purchasing convenience, and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon, and PPD. Our Innovative Laboratory technologies & Services makes it easier for customers .

Antibody team The antibody team is involved in development and engineering of antibodies, with a deep focus on reagent quality and specificity. The core activities of team include design, development, purification, conjugation and testing of antibodies in a variety of immunoassay applications using state of the art technologies. The goal of the program is advanced product development and creation of product specific information to promote research use. Role & Responsibilities Role: To be an integral part of an antibody development team with a focus on performance and specificity using innovative molecular, protein, and cell biology methods.

Contribute in a fast- paced environment towards Antibody development & Validation Project leadership role in new antibody development programs with experimental planning and execution to meet the program milestone. Lead team of scientists in matrix style operation, provide technical and operational supervision. Mentoring and training junior scientists. Design and experimental execution, interpreting data and data presentation to the stakeholders. Drive ideation within teams to enable development of successful protocols for effective transfer to operation teams. Serve as subject matter expert in antibody discovery and biophysical characterization to provide inputs and guidance towards driving innovation and cross team collaborations. Knowledge of product commercialization processes from concept to launch including early feasibility, development, and validation phases. Good scientific writing skills, establishing technical protocols for effective transfer to operations teams. Good documentation practice is a must to maintain data integrity and accuracy. Delivering high quality results according to project schedule in support of product commercialization from concept to launch including early feasibility, development and validation phases. Candidate Requirement: Education & Experience levels: Applicants should have a PhD with greater than 7 years’ experience in a life sciences field with a strong focus on protein biology. Minimum 3-4 years of Industrial experience is required. Prior people management experience is preferred. Nature of experience: Extensive experience in the antibody development and engineering including hybridoma, single B cell, phage display and other recombinant antibody platforms Extensive experience and familiarity with antibody or protein design and biophysical characterization using state of the art methodologies including SPR and BLI Expertise in antibody screening and characterization methods including affinity measurements and epitope binning Experience in the field of molecular biology, protein expression, protein purification, protein-protein interaction, protein structure -function relationships, and immunogen designs Proficient in molecular biology workflows such as