Analytical Development Scientist (HPLC)

Work Schedule Standard (Mon-Fri) Environmental Conditions Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.) Job Description Do you have a passion for innovative ideas and groundbreaking discoveries? With over $1 billion invested annually in R&D, at Thermo Fisher Scientific you’ll help solve some of the world’s toughest challenges, from giving cancer patients hope, ensuring safe drinking water and helping law enforcement tackle cases through forensics. We empower our teams to put science into meaningful action and give our R&D colleagues the autonomy, resources, and tools they need to take science a step beyond. Location : On-site Bedford, MA. Relocation assistance is NOT provided.  Must be legally authorized to work in the United States without sponsorship. Must be able to pass a comprehensive background check, which includes a drug screening. Discover Impactful Work: We are seeking an innovative and highly motivated Analytical Development Scientist to join our R&D organization. In this role, you will contribute to the development and commercialization of next-generation analytical technologies with a primary focus on HPLC products and processes supporting critical to quality attributes in the biotechnology and biopharmaceutical industries. You will work in a collaborative, cross-functional environment to develop robust products, characterize product performance, and accelerate new product introductions that address critical customer needs. Experience or familiarity with analytical chromatography product development is highly desirable.

Develop, optimize, and apply analytical HPLC methods to characterize product performance and support new product development. Design and execute experiments to evaluate product attributes relevant to regulated bioprocessing, biologics development, and drug-quality monitoring. Develop analytical strategies to assess critical-to-quality attributes, including purity, aggregation, charge variants, identity, concentration, or other relevant product and process attributes. Generate, analyze, and interpret complex analytical datasets to guide technical decisions, product requirements, and development strategy. Evaluate HPLC product performance across relevant use conditions, sample types, workflows, and customer applications. Support product development activities, including feasibility studies, prototype evaluation, design verification, process optimization, technology transfer, and commercialization. Collaborate closely with Product Management, Applications, Manufacturing, Quality, Regulatory, Commercial, and other R&D teams throughout the product lifecycle. Support method transfer, manufacturing validation, and new product introduction activities through robust experimentation and clear documentation. Author technical reports, protocols, SOPs, test methods, presentations, and other scientific documentation. Identify technical risks, troubleshoot analytical challenges, and adapt experiments based on emerging data. Contribute to innovation initiatives by identifying new applications, technologies, customer needs, and product opportunities. Present technical findings and recommendations to internal stakeholders and, when appropriate, external customers. How You Will Get Here:

Ph.D. or M.S. with 3+ years of experience in Analytical Chemistry, Biochemistry, Chemical Engineering, Biotechnology, Pharmaceutical Sciences, or a related scientific field preferred; Bachelor's with 5+ years of experience in Analytical Chemistry, Biochemistry, Chemical Engineering, Biotechnology, Pharmaceutical Sciences, or a related scientific field acceptable. Hands-on experience with analytical chromatography systems, preferably HPLC or UHPLC. Strong understanding of analytical chromatography principles, method development, method optimization, and data interpretation. Experience developing or