Sr. Principal Scientist, Clinical Operations Immunology Lead

Translational Medicine (TMed) drives early clinical development of novel therapeutics by partnering with Discovery Sciences and Late-Stage Clinical Research to translate scientific discoveries into human proof-of-concept and advance the most promising candidates through the pipeline to patients. Our Clinical and Operations organization designs and executes clinical pharmacology strategies spanning first-in-human studies through proof-of-biology/proof-of-concept and into late-stage development, supporting worldwide marketing applications and lifecycle management. In a competitive external landscape and fast-paced internal environment, the Immunology Clinical Operations Lead position provides both strategic and operational leadership across early immunology programs, ensuring timely, high-quality execution of clinical studies and clinical pharmacology strategies worldwide. The successful candidate will telescope between strategy and hands-on execution across a portfolio of diverse modalities (e.g. peptides, small molecules, biologics), and partner cross-functionally to develop the needed expertise to successfully advance programs to key inflection points in development. This role is equivalent in level to a Senior Director position. All candidates located within a 50-mile driving radius of the site will be required to come onsite on a hybrid schedule. Candidates outside of the 50-mile radius are expected to travel onsite on a regular monthly basis. Why join us: Take a clinical operations leadership role at the intersection of discovery and clinical development to advance novel immunology therapeutics from bench to bedside. Influence strategy, build teams, and deliver high-impact clinical programs that shape the future of patient care.

Co-own and execute the early clinical development strategy for the immunology portfolio with the Head of TMed Immunology Provide comprehensive strategic planning and operational oversight for immunology clinical programs and trials to maximize operational feasibility, efficiency, and ensure consistency and quality across the portfolio Build global network of immunology sites and foster relationships with key investigators for Ph1b/2a patient trials to deliver on clinical program goals Serve as the deep subject matter expert and issue escalation point for early immunology clinical operations Ensure appropriate resources, competencies, and partnerships are in place to meet objectives Critically review strategy and clinical program documents (development plans, investigator’s brochures, protocols, etc.), providing scientific and operational insight to ensure best path forward Partner with Business Development and Licensing to evaluate internal and external opportunities that align with portfolio strategy Actively participate in annual and quarterly planning cycles: identify risks, develop and execute mitigation plans, and track performance metrics and outcomes Ensure immunology data integrity across organization (Book of Business, CTMS, etc.) Build and sustain strong cross-functional relationships (country operations, clinical supplies, data management, regulatory, etc.) across departments, divisions, and geographies Foster the people pipeline: Attract, coach, mentor, and retain talent; provide performance management support; act as ‘player-coach’ to enrich group skillsets. Potential for people management. Represent TMed on enterprise strategic initiatives and lead continuous-improvement efforts that increase clinical efficiency and scientific impact Serve as a member of the TMed Clinical Operations leadership team and contribute to shaping department strategy Education Requirement Degree in Life Sciences with one of the following experience combinations: Bachelor’s degree + ≥16 years related experience, OR Master’s degree + ≥15 years related experience, OR PhD/PharmD + ≥12 years related experience Related Experience Includes: pharmaceutical