Sr. Manager Clinical Supply Operations

Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life-threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy through a portfolio of innovative technologies, including autologous, allogeneic, and in vivo cell therapy approaches. Our research spans chimeric antigen receptor T-cell (CAR-T), T-cell receptor (TCR-T), natural killer (NK) cell-based therapies, and other emerging platforms designed to transform the treatment of serious diseases. From our global network of research and development sites, we are committed to discovering and developing safe, effective, and cutting-edge therapies for patients worldwide.

Legend Biotech entered into a global collaboration agreement with Johnson & Johnson to jointly develop and commercialize CARVYKTI® (ciltacabtagene autoleucel; cilta-cel). Through this strategic partnership, we combine complementary expertise and capabilities to advance innovative immunotherapies for patients living with multiple myeloma.

Legend Biotech is seeking a Sr. Manager Clinical Supply Operations as part of the Technical Operations team based in Somerset, NJ.

Legend Biotech is seeking an experienced and driven Sr. Manager- Clinical Supply Operations to join our Technical Development team. This role will report to the Director of Patient Supply Strategy & Operations and be responsible for supporting hands on execution of global patient supply activities for early clinical Cell and Gene Therapy programs (Allogenic and In-Vivo). This role will coordinate investigational product planning, packaging and labeling, distribution, inventory, quality release, returns, reconciliation, and destruction across clinical sites, depots, CROs, and external vendors. The successful candidate will bring strong operational discipline, systems proficiency, vendor coordination, and cross-functional partnership to help ensure continuous, compliant supply of clinical trial material.

• Coordinating supply activities across multiple studies, countries, sites, depots, vendors, and systems.

• Maintaining accurate inventory visibility while protocols, enrollment forecasts, shelf life, and country requirements evolve.

• Managing temperature excursions, expiry risk, documentation gaps, shipment issues, and competing operational priorities.

• Translating cross-functional inputs into timely, practical clinical supply actions and clear follow-up.

• Reliable execution of clinical supply plans, packaging