Manager - Exploratory Analysis (Hybrid)

About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube.

The Manager - Exploratory Analysis provides statistical expertise to support the research and development organizations for drug discovery, target identification/verification, non-clinical and clinical biomarker exploration to characterize subgroups of patients or markers of disease progression and treatment response for precision medicine. The manager works independently with discovery researchers, translational scientists and clinicians in the design, collection, analysis and reporting of multi-dimensional biomarker data from Discovery to late stage clinical development to enable objective decision-making for each drug development program. Major Job Responsibilities: If assigned, working independently as a point of contact for DIVES to collaborate with translational biomarker scientists and clinicians in the design, analysis and reporting of biomarker and assay studies in association with early and late phase clinical trials. The typical analysis includes pharmacodynamic biomarker analysis, safety biomarker analysis, prognostic and predictive biomarker identification and development, bioassay and companion diagnostic test development, patient subgroup identification based on biomarkers and clinical variables. Accountable for data integrity of the responsible statistical analysis and deliverables. Providing expertise to design, analysis and reporting of biomarker-based clinical trials or other scientific research studies. Independently developing biomarker section of clinical trial protocols or biomarker analysis plans. Implementing sound statistical methodology in scientific investigations. Working independently as a point of contact for DIVES to collaborate with scientists in discovery and translational science units in the design, analysis and reporting of in vitro, in vivo pharmacology studies, and human clinical trials. Identify markers and signatures from internal/external omics/imaging and other biomarker data for target identification, mechanism of action, resistant mechanism, disease progression, patient selection and stratification for precision medicine. Independently perform statistical analyses as per the biomarker analysis plan. Independently identifying issues arising in the study design; conducting and proposing scientifically sound approaches. Evaluating appropriateness of available software for planned analyses and assessing needs for potential development of novel statistical methodology. Fully accountable for statistics/data presentation and inference. Collaborating in publication of scientific research. Ensuring that study results and conclusions are scientifically sound, clearly presented, and consistent with statistical analyses provided. Clearly explaining statistical concepts, enabling non-statisticians and biomarker collaborators to use existing tools and interpret results better.

Minimum Qualifications: MS (with 6+ years of experience) or PhD (with 2+ years of experience) in Statistics, Biostatistics, or a highly related field, with some applied consulting or research experience on topics related to pharmaceutical research, bioinformatics, target identification, biomarkers (highly preferred), and subgroup identification. Experience with pharmaceutical, clinical trial and/or healthcare statistics Preferred Qualifications: Experience working on discovery/pre-clinical studies Experience in