Senior Specialist, Quantitative Pharmacology and Pharmacometrics - Cardiometabolic and Ophthalmic Diseases

The Quantitative Pharmacology and Pharmacometrics (QP2) Department of our Company's Research Laboratories in West Point, PA / Rahway, NJ is seeking a curious and collaborative Senior Scientist to support our rapidly expanding cardiometabolic and ophthalmology pipelines. As a senior specialist you will be part of a cross-functional teams of experienced scientists to discover and develop novel therapeutic agents of various modalities for cardiometabolic and ophthalmic diseases. The senior specialist is a skilled quantitative scientist, with a good understanding of the strategic elements of drug discovery and development. The senior specialist should demonstrate collaborative work spirit and good communication skills. Within QP2, you have a unique opportunity to accelerate your professional career as a quantitative drug developer taking advantage of our end-to-end pipeline support in one of the world’s most research-intensive biopharmaceutical companies. Responsibilities: · Contribute to the development of model-based strategies (translational PK/PD strategies, mechanistic model, POPPK/PD, clinical trial simulations, etc) for quantitative analyses, within and across development programs and/or departments, to inform and optimize drug discovery and all phases of drug development including, but not limited to dose selection, clinical trial design, and go/no-go decisions. · Represent QP2 on cardiometabolic and ophthalmology discovery, early clinical development and late clinical development teams, leveraging quantitative approaches to drive streamlined development of programs within our growing portfolio. · Collaborate with other functional areas, as well as with external vendors and partners, on activities related to study design, protocol development, study execution, reporting and interpretation of data. Required: · A Ph.D. or equivalent degree OR a PharmD or equivalent degree with at least 2 years of experience OR an MS or equivalent degree with at least 4 years of experience, where “experience” means having a record of increasing responsibility and independence in a similar role in pharmaceutical drug development, regulatory agency, or academia. · Educational background in biopharmaceutics, pharmaceutical sciences, pharmacometrics, chemical/biomedical engineering, or a related field. · Experience in performing population PK, PK/PD analyses using standard pharmacometrics software (e.g. NONMEM, Monolix, Phoenix, etc.). · Good written and verbal communication, interdisciplinary collaboration, and problem scoping and planning. Preferred: · Knowledge in cardiometabolic and/or ophthalmology clinical drug development programs · Skills in experimental design, mathematical problem solving, critical data analysis/interpretation, and statistics. · Scientific understanding of biopharmaceutical and ADME properties of small molecules and/or biologics Required Skills: Clinical Study Design, Clinical Trial Designs, Clinical Trials, Database Design, Data Engineering, Data Modeling, Data Science, Data Visualization, Interdisciplinary Collaboration, Machine Learning (ML), Pharmacodynamics, Pharmacokinetics, Pharmacotherapeutics, Waterfall Model Preferred Skills: Current Employees apply HERE Current Contingent Workers apply HERE US and Puerto Rico Residents Only: Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process. As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for