Scientist - LC-MS Specialist/Analytical Chemistry

Career Category Research Job Description Amgen is one of the world’s leading independent biotechnology companies. For four decades, Amgen has pioneered biotechnology breakthroughs to bring   state-of -the-art   me dicines from laboratory to the patient. Amgen Research Copenhagen (ARC) ,   through our DNA Encoded Library (DEL) technology , is   contributing significantly to Amgen’s many small   molecule drug discovery projects from hit discovery all the way to drug candidate selection.   We are currently seeking a   candidate   to join a team that   operates , supports, troubleshoots, and   maintains   analytical instruments, while providing expert instrument guidance to user s running   samples. In addition, the candidate will support the effective use of various LC–MS software packages.    If you are passionate, analytical, resourceful ,   practical,   goal-oriented, open-minded, conscientious, willing to go the extra mile, enjoy working in the lab in a dynamic environment, and have a desire to contribute to groundbreaking scientific research within a new field of drug discovery, we may have a position for you.   As a member of the Analytics team ,   you will help us setup and operate LC -MS   systems and various automated sample preparation equipment t o ensure   high-throughput acquisition, analysis and purification of small molecule including oligo conjugates to deliver   high-quality   data, take part in method development and implementation of new analytic instruments. The position will primarily involve maintenance and setup of LC-MS systems, but also method development and testing of new setups. You will be working cross-functionally with internal groups specializing in DEL-technology, parallel synthesis, medicinal chemistry and biology, and you will   participate   with your analytical   expertise   in the process of identifying   and purifying various compounds.   Specifically, tasks will include:   ·       Daily care of ARC analytical and prep LC-MS.    ·       Keeping LC and MS instruments, including CLND   detectors , in excellent operational state.   ·       Software support for all LC and MS based software package   ·       Supervision of LC-MS users   ·       Purification of oligo conjugates and other compounds on LC systems   ·       Keeping track of spare parts for all instruments   We offer a highly rewarding and stimulating environment in a world-class drug discovery organization.   The position is based across our two Østerbro offices, 1.3 km apart,   about 4   minute s by   bike.   The employee will report t o   Scientific   Associate   Director, Michael   Godskesen. For further informa tion con tact HR   Sr Manager,   Rachel Allen (Rallen03@Amgen.com)      Qualifications:   Preferably, the candidate should hold an M.Sc. or B.Sc. degree in a relevant technical or scientific discipline and have at least three years of experience   maintaining   and operating LC instruments from mult iple s uppliers. Laboratory technicians with at least ten years of relevant experience and well-documented training may also be considered.   The ideal candidate will have:   ·       Proficiency in running analytical a s   well as preparative samples on various LC -MS   platforms   ·       In depth understanding of liquid chromatography and Mass Spectrometry   ·       On hands experience working and maintenance of different LC-MS systems   ·       Competence related to manual and automated sample preparation   ·       Proficiency in Agilent   ChemStation   and   MassHunter   software   ·       Familiarity   with Waters Ma ssLynx software   ·       Knowledge of Shimadzu LabSolutions software   ·       Experience working with third party analytical software ACD Labs,