Senior Principal Clinical Research Specialist - NV - Irvine, CA; Lafayette, CO or Fridley, MN (Onsite)

We anticipate the application window for this opening will close on - 19 Sep 2026   Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first — developing innovative medical technologies that improve the lives of 72+ million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact. A Day in the Life The Neurovascular Clinical Research team supports the global clinical development of therapies designed to treat stroke and other neurovascular conditions. This team partners across Clinical, Research & Development, Regulatory, Quality, Health Economics & Reimbursement, Marketing, and Medical Affairs to generate clinical evidence that supports product development, regulatory submissions, and commercialization activities. Primary preference is for candidates based in Fridley/Mounds View, Minnesota; Irvine, California; or Lafayette, Colorado. This role follows a flexible onsite work model with a minimum of four days per week onsite. Travel requirements are expected to be approximately 25% based on business needs.                     Check us out on LinkedIn: Medtronic Neurovascular The Senior Principal Clinical Research Specialist is a strategic clinical research leader responsible for independently leading complex clinical studies and providing oversight of clinical research programs supporting Medtronic Neurovascular therapies. This individual will drive study execution, manage multiple workstreams, influence cross-functional stakeholders, and serve as a key clinical representative to leadership, investigators, physicians, and external partners. The role requires the ability to rapidly assume ownership of high-visibility programs and communicate clinical strategy and study progress to executive leadership.

Lead the planning, execution, and oversight of complex clinical studies and clinical development programs supporting Neurovascular therapies. Provide strategic leadership for one or more large clinical studies, ensuring achievement of study objectives, timelines, quality standards, and business priorities. Manage multiple studies, workstreams, and competing priorities simultaneously in a fast-paced environment. Develop and execute clinical evidence generation strategies that support regulatory, commercial, and product development objectives. Partner closely with Clinical, R&D, Regulatory Affairs, Quality, Medical Affairs, Marketing, Health Economics & Reimbursement, and other stakeholders to drive study success. Serve as a key liaison with physicians, investigators, external clinical partners, and other stakeholders throughout study execution. Present clinical study strategy, progress, risks, and outcomes to senior leaders and executive stakeholders. Author and review clinical, scientific, and regulatory documentation, including study protocols, clinical study reports, publications, presentations, and submission support materials. Interpret, analyze, and communicate complex clinical data and study outcomes to technical and non-technical audiences. Lead publication and dissemination activities in collaboration with physician investigators, key opinion leaders, and internal stakeholders. Monitor emerging scientific literature, competitive developments, and evolving clinical evidence within the neurovascular therapeutic area.

Bachelor's degree in a technical discipline and 10+ years of relevant clinical research or medical device experience, or an advanced degree with 8+ years of relevant experience. Demonstrated experience independently leading complex clinical studies or clinical development programs. Proven experience owning study strategy, execution, timelines, stakeholder management,