Intern – Research – Protein Therapeutics, Computational Biologics Engineering

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.   Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact.   We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.

Intern – Research – Protein Therapeutics, Computational Biologics Engineering As a Gilead intern you will contribute to high-impact meaningful projects that will not only further advance our company’s mission but will allow you to gain real world experience at one of the most innovative organizations in the world.  You will also have opportunities to participate in special events including professional development and leadership presentations, social/network building activities and local community volunteer programs. This opportunity will involve exploring how emerging generative protein design approaches can be applied to biologics discovery and development. The intern will contribute to the design and evaluation of antibody- and miniprotein-based therapeutic candidates while helping develop computational workflows for candidate generation, prioritization, and analysis. Research activities may include a combination of AI/ML methods, molecular modeling, structure-based design, and integration of experimental feedback to guide future design cycles. Key Responsibilities will include, but are not limited to the following: Apply generative protein design workflows to produce and evaluate biologic-based binders against therapeutically relevant targets. Build reproducible Python-based workflows for large-scale protein design, structural analysis, candidate ranking, and data visualization. Apply physics-based modeling tools (e.g., Rosetta, MOE, Schrödinger) to assess binding energetics and developability properties. Explore protein language model representations and lightweight ML models that consider protein sequence, structure, and physics-based features to predict and prioritize candidate properties. Advance top designs to recombinant expression and experimental characterization (e.g. titer, BLI, DSF). Document workflows, results, and recommendations clearly for use in future protein-engineering campaigns. Showcase your work with a final presentation (PPT) near the conclusion of your internship Required Qualifications: Must be at least 18 years of age at the start of the internship. Must be enrolled full‑time in a Bachelor’s, Master’s, MBA, JD or PhD program at a nationally accredited U.S. college or university, with continued full‑time enrollment required in the Fall semester following the internship. Must be currently enrolled as an undergraduate (freshman, sophomore, junior, or senior) or as a graduate/doctoral student. Must have a minimum overall cumulative GPA of 2.8 at the time of application and hire (official transcripts will be requested). Must be independently authorized to work in the United States now and in the future (current or future work authorization must not require school or employer sponsorship) official transcripts