Senior Manager Portfolio Management

Build our future together: The Senior Manager, Portfolio Management is responsible for owning key portfolio management processes and supporting the execution of portfolio planning and review activities across Global Development. This role serves as a strategic partner to the Director of Portfolio Management, translating complex portfolio information into actionable insights, facilitating cross-functional alignment, and driving the execution of portfolio operating processes that support informed decision-making. The successful candidate will independently lead assigned portfolio management workstreams, develop executive-level analyses and communications, and partner with stakeholders across Clinical Development, Research, Finance, Operations, and other functions to improve portfolio visibility, planning, and execution. Portfolio review frameworks, planning activities, portfolio reporting, prioritization discussions, and portfolio operating processes are recurring responsibilities within the team's work. When & where: Primary Location: Tarrytown, NY Additional Locations: Warren, NJ or Cambridge, MA Discover your role: Portfolio Review & Planning Execution Own the planning and execution of assigned portfolio reviews and portfolio planning activities, including timelines, deliverables, stakeholder engagement, content integration, and meeting readiness. Lead cross-functional preparation efforts to ensure portfolio discussions are supported by accurate, timely, and decision-relevant information. Partner with stakeholders across Clinical Development Units, Development Program Management, Resource Management, Finance, and other functions to consolidate portfolio inputs and ensure alignment on key messages and discussion topics. Support the Director of Portfolio Management in enterprise-level portfolio reviews and other strategic portfolio initiatives. Portfolio Assessment & Decision Support Develop portfolio analyses that identify execution risks, portfolio constraints, milestone impacts, prioritization challenges, and opportunities requiring management attention. Assess portfolio trends and emerging issues to support discussions regarding resource allocation, portfolio trade-offs, and execution planning. Develop clear recommendations, discussion materials, and supporting analyses for leadership review. Support the Director of Portfolio Management in evaluating broader portfolio scenarios, prioritization discussions, and portfolio optimization opportunities. Portfolio Operating Process Ownership Own assigned portfolio management processes and ensure consistent execution, defined deliverables, and ongoing process improvement. Establish and maintain standardized templates, workflows, and operating procedures that improve efficiency, transparency, and consistency across portfolio activities. Monitor process performance and recommend enhancements to improve the quality and effectiveness of portfolio management activities. Support the Director of Portfolio Management in evolving portfolio management capabilities and operating models. Executive Communications & Portfolio Reporting Develop executive presentations, portfolio summaries, briefing materials, and leadership communications that synthesize complex portfolio information into concise and actionable insights. Own recurring portfolio reporting activities, including status updates, portfolio summaries, milestone tracking, and leadership communications. Track and communicate key portfolio developments, risks, actions, and outcomes arising from portfolio review discussions and planning activities. Cross-Functional Portfolio Partnership Serve as the primary portfolio management partner for assigned functions, portfolio segments, or review processes. Lead cross-functional working sessions to align stakeholders on portfolio assumptions, risks, dependencies, and recommendations. Build productive relationships across stakeholder groups and facilitate resolution of issues affecting portfolio