Supply Chain Manager
Amgen
- Location
- US California Los Angeles
- Work model
- On-Site
- Level
- Mid
- H-1B history
- 137 approvals (FY2023)
- Posted
- Sep 15, 2026
Skills
About this role
Career Category Operations Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Supply Chain Manager What you will do Let’s do this. Let’s change the world. In this vital role you will establish and manage the end-to-end external supply chain for Amgen’s new product portfolio. The Supply Chain Manager will drive supply planning, material readiness, and delivery of pre-clinical, clinical, and PPQ products manufactured at Amgen’s Contract Manufacturing Organizations (CMOs). The role will partner with Global Supply Chain, Product Teams, Amgen Contract Manufacturing, CMOs, and other cross-functional partners to design and implement supply chain solutions for new external manufacturing sites. The Supply Chain Manager will translate program demand and manufacturing requirements into executable supply plans, assess supply constraints and risks, and coordinate mitigation actions to enable timely decisions and reliable supply. The goal for this position is to deliver supply in the right product quantity to the right location at the right time, while optimizing inventory and cost within contractual terms, eliminating stock-out and scrap exposure, and improving the overall supply risk profile. Driving and supporting site-level implementation of Amgen’s integrated business processes, including Plan-to-Stock, Order-to-Cash, and handoff processes with CMOs and internal functions. Developing and maintaining executable supply plans and conducting capacity and inventory scenario analyses to evaluate options and inform program decisions. Assessing CMO supply chain readiness, including capabilities, manufacturing capacity, lead times, critical raw material requirements, and other constraints; coordinating mitigation actions to protect supply continuity. Overseeing timely, compliant execution of assigned site-level supply chain operations and financial flows, including inventory, order and invoice management, and coordination of material movements. Establishing and maintaining applicable SAP and RapidResponse master data and ensuring accurate, compliant system transactions. Ensuring applicable operating standards and supply chain requirements for technology transfer and new product introduction are implemented and sustained at managed sites. Partnering across Supply Chain, Quality, Finance, Process Development, Operations, Global Distribution, and other functions to develop and communicate analyses, recommendations, and presentations to cross-functional and leadership audiences. Serving as a supply chain representative for change controls, special projects, and continuous-improvement initiatives. Key activities Depending on the assigned product portfolio, program stage, site model, and functional ownership, the AXP Supply Chain Manager may carry out, coordinate, or support the following activities in accordance with established processes and procedures.