Sr. Manager Engineering

Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life-threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy through a portfolio of innovative technologies, including autologous, allogeneic, and in vivo cell therapy approaches. Our research spans chimeric antigen receptor T-cell (CAR-T), T-cell receptor (TCR-T), natural killer (NK) cell-based therapies, and other emerging platforms designed to transform the treatment of serious diseases. From our global network of research and development sites, we are committed to discovering and developing safe, effective, and cutting-edge therapies for patients worldwide.

Legend Biotech entered into a global collaboration agreement with Johnson & Johnson to jointly develop and commercialize CARVYKTI® (ciltacabtagene autoleucel; cilta-cel). Through this strategic partnership, we combine complementary expertise and capabilities to advance innovative immunotherapies for patients living with multiple myeloma.

Legend Biotech is seeking a Sr. Manager Engineering as part of the Facilities and Engineering team based in Raritan, NJ.

The Senior Manager, Engineering, is responsible for leading a multidisciplinary engineering organization supporting commercial CARVYKTI® cell therapy manufacturing operations. This role provides strategic and technical leadership for the lifecycle management of manufacturing equipment and systems, process optimization initiatives, manufacturing troubleshooting, cost of goods (COGs) reduction programs, and management of a Facilities Investigation Team responsible for non-conformance investigations.

The successful candidate will lead a team of engineers and investigators that ensure manufacturing equipment reliability, operational excellence, regulatory compliance, and continuous improvement across the cell therapy manufacturing process. This position serves as a key partner to Manufacturing, Quality, Validation, Maintenance, MSAT, Supply Chain, and Regulatory functions to ensure uninterrupted production and continuous advancement of manufacturing capabilities.

• Lead, develop, and mentor a team of engineering professionals responsible for cell therapy manufacturing operations and equipment support.

• Establish team goals, performance objectives, and development plans aligned with site and business priorities.

• Foster a culture of safety, accountability, technical excellence, innovation, and continuous improvement.

• Build organizational capabilities to support commercial growth, technology transfer