Principal Process Engineer, Advanced Manufacturing Technical Lead

We anticipate the application window for this opening will close on - 23 Sep 2026   Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first — developing innovative medical technologies that improve the lives of 72+ million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact. A Day in the Life Principal Process Engineer in AME organization.                     As a Principal Process Engineer on Medtronic’s Advanced Manufacturing Engineering (AME) team, you will combine broad, hands-on engineering experience with strong technical leadership to support the development, commercialization, and scale-up of life-saving medical technologies.     In this role, you will apply a well-rounded background across manufacturing processes, equipment, materials, process development, validation, and continuous improvement to solve complex challenges and guide engineering decisions. You will connect product requirements with practical manufacturing solutions, supporting programs from early development through production.     You will also help strengthen the team’s technical capabilities by mentoring engineers, coaching structured problem-solving, sharing knowledge, and guiding cross-functional teams. Success requires technical depth, the ability to work across engineering disciplines, and a collaborative leadership approach that builds confidence, accountability, and sound engineering judgment in others.     At Medtronic, we bring bold ideas forward with speed and decisiveness to put patients first in everything we do. In-person exchanges in a manufacturing environment are invaluable to our work. This role requires working onsite a minimum of five days per week to support professional growth and cross-functional collaboration as we work together to engineer the extraordinary.

Provide hands-on technical leadership across process development, equipment selection and integration, process characterization, validation, technology transfer, and manufacturing optimization.   Apply broad engineering knowledge to evaluate how materials, equipment, tooling, process parameters, and product design interact to influence manufacturing performance.   Lead complex engineering initiatives from concept through implementation, balancing product requirements, quality, manufacturability, scalability, cost, and project timelines.   Partner with R&D, Quality, Operations, Supply Chain, Regulatory Affairs, and external partners to resolve technical challenges and support successful new product introductions and ongoing manufacturing.   Evaluate manufacturing approaches and emerging technologies, including automation and digital manufacturing capabilities, and recommend solutions appropriate to the application.   Lead process characterization and establish effective process controls using Design of Experiments (DOE), Statistical Process Control (SPC), capability analysis, and data-driven decision-making.   Guide process risk assessments, validation strategies, and execution of IQ/OQ/PQ activities in accordance with applicable quality system and regulatory requirements.   Lead investigations into complex manufacturing issues, working directly with teams to identify root causes, evaluate solutions, and implement sustainable corrective and preventive actions.   Mentor and coach engineers across experience levels, helping them strengthen technical skills, troubleshooting approaches, engineering judgment, and project ownership.   Review engineering studies, technical documentation, and proposed solutions; provide constructive feedback and help teams understand the reasoning behind technical decisions.   Foster a collaborative