Senior Director, Global Medical Affairs

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.  Centessa Pharmaceuticals, a wholly subsidiary of Eli Lilly and Company is advancing a portfolio of high conviction programs with strong biological validation.  Our asset-centric model offers a unique R&D logic that has been applied by single asset companies to improve productivity. This operating model has minimal centralized infrastructure, reduced hierarchy, and exclusive focus on data driven capital allocation.    Our teams are uniquely incentivized to expeditiously interrogate key scientific hypotheses. We believe the asset-centric model can lead to improved success rates for programs with greater speed and modest costs.   Description of Role The Senior Director, Global Medical Affairs, will serve as the Global Medical Affairs Lead for Centessa's lead orexin receptor 2 agonist program. This strategic leadership role is responsible for developing and executing the global medical strategy across the product lifecycle, with a primary focus on launch readiness, scientific leadership, evidence generation, external engagement, and cross-functional partnership. The successful candidate will have demonstrated experience leading global medical affairs activities for one or more successful product launches and possess a strong track record of partnering with commercial, market access, HEOR, clinical development, regulatory affairs, patient advocacy and regional medical teams to deliver integrated launch strategies. The individual will serve as the medical voice of the asset, ensuring that scientific evidence, stakeholder insights, and patient needs are incorporated into key business decisions. This role reports to the Head of Medical Affairs and will partner closely with senior leadership across the organization.

Global Medical Strategy & Leadership Lead the global medical affairs strategy and tactical execution plan for cleminorexton Serve as the Global Medical Affairs Lead and core member of the cross-functional asset team Ensure alignment of medical strategy with corporate objectives, clinical development milestones, and commercialization plans Establish long-range medical affairs planning to support regulatory approvals, launch readiness, and lifecycle management Identify emerging scientific opportunities, evidence gaps, and stakeholder needs to inform future development Global Launch Excellence Lead medical launch preparedness activities across major global markets Partner with commercial, market access, HEOR, regulatory affairs, and regional medical teams to develop integrated launch strategies Collaborate with medical affairs colleagues to ensure deliverables are aligned with strategy and launch timelines, including scientific platforms, training content, medical information resources, publications, congress activities, and insights generation Support pre-launch and launch planning activities, including collaborating with HEOR and market access for global payer engagement strategies and value communication External Scientific Engagement Build and maintain relationships with global key opinion leaders, investigators, professional societies, and patient advocacy organizations. Lead scientific advisory boards, expert consultations, and other insight-gathering initiatives. Represent Centessa at major scientific congresses and industry meetings. Serve as a