Finance Sr. Manager

Career Category Finance Job Description Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Finance Sr. Manager What you will do Let’s do this. Let’s change the world. In this vital role, Amgen is seeking a highly motivated and experienced finance professional to join the North Carolina Drug Substance Operations Financial Planning and Analysis (FP&A) team. In this role, you will partner closely with site and finance leadership to deliver high-quality financial planning, reporting, and analytics for ANC site operations. This role is designed for a finance member with deep manufacturing experience, strong understanding of Cost of Goods Manufactured (COGM) planning, and the ability to connect operational performance to business strategy. The ideal candidate brings a balanced combination of technical financial expertise, strategic thinking, process improvement orientation, and comfort leveraging technology to improve insight, efficiency, and decision-making. Develop the Cost of Goods Manufactured (COGM) budget, forecasts, and long-range plans for ANC site operations by applying a deep understanding of the operational and financial drivers that shape manufacturing performance. Translate key assumptions—including COGM cost elements, Net vs. Inventory determination, operating expenses, production plans, capacity assumptions, and drug substance manufacturing parameters—into accurate and robust financial plans. Partner closely with Site & Global teams such as Supply Chain, Manufacturing, Accounting, Procurement, to identify, validate, challenge, and align the underlying planning assumptions. Ensure financial plans accurately reflect operational realities while providing meaningful insights to support business decisions and long-term strategic planning. Implement and maintain a model for multi-plant site allocation methodology. Use technology, advanced analytics, and automation tools to deliver timely, accurate, and actionable insights for senior leadership. Understand and apply standard costing structure and methodology to provide meaningful insights during manufacturing variance reviews and annual standard costing execution. Support financial analysis and scenario modeling for new product introductions, technology transfer programs, production plan options and other strategic site initiatives. Oversee monthly and quarterly actual results versus forecast and plan for assigned functions; including variance analysis and senior leadership level commentary and business performance insights. Partner with site key stakeholders on capital investment business cases, cost optimization initiatives, and productivity program implementation. Develop a strong understanding of Amgen financial policies, internal controls, financial discipline and compliance requirements; educate and support site stakeholders in applying them effectively. Support process improvement