Principal Data Engineer

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Principal or Staff Data Engineer to join our IOPS IT team, building the data infrastructure and pipelines that power data-driven decision-making across the organization. In this role, you will architect and optimize scalable data solutions, drive technical standards, and mentor junior engineers — while collaborating with partners across Manufacturing, Quality, and IT to deliver reliable, governed, and innovative data capabilities. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide. When & where: Location: Raheen, Limerick County Work model: Monday - Friday 8am - 4:30pm What you’ll do: Architect and optimize secure, scalable data pipelines (ETL/ELT) for real-time and batch processing, integrating diverse data sources and establishing CI/CD practices and fault-tolerant systems Designing data lake and warehouse solutions that ensure large datasets are organized, accessible, and of high quality; implement data modeling and schema design aligned to business needs Monitoring pipeline performance, troubleshooting issues, and implementing observability and alerting systems to maintain reliability across the data platform Ensuring adherence to data governance policies and industry regulatory requirements including 21 CFR Part 11, GxP, and CSA; maintain comprehensive system documentation Leveraging GenAI and MCP/orchestration platforms to enhance team efficiency and drive infrastructure innovation Defining technical standards and design complex data engineering solutions that scale across the organization Mentoring junior engineers, contributing to team capability growth, and serving as a technical leader across data engineering initiatives The environment and physical rhythms of this role: Strong programming skills in Python, Java, or Scala; deep SQL expertise and relational database experience required Experience with NoSQL and big data technologies such as Hadoop, Spark, and Kafka; stream processing experience (Kafka, Flink) a plus Experience with workflow orchestration tools (Airflow, Luigi, Prefect, or similar) and containerization technologies required Familiarity with Biotech Enterprise Systems including MES, LIMS, and QMS preferred Knowledge of data security, compliance requirements, and regulatory standards including CFR Part 11 and GxP in regulated environments Cloud certifications a plus Let’s find out if we’re a fit: BS/BA in Computer Science, Bioinformatics, or a related field; Master's degree preferred Principal: 8+ years of relevant experience, including 1+ years in biotech, pharmaceutical, or life sciences and 3+ years on cloud platforms (AWS or Azure) Staff: 10+ years of relevant experience, including 3+ years in biotech, pharmaceutical, or life sciences and 5+ years on cloud platforms (AWS or Azure) Thrive today. Grow tomorrow. #IRELIM #JOBSIEST #LI-Onsite Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all  qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation