Lead Operational Strategy & Execution - Data Analytics & AI
McKesson
- Location
- USA, TX, Irving
- Work model
- On-Site
- Level
- Senior
- H-1B history
- 49 approvals (FY2023)
- Posted
- Sep 18, 2026
About this role
McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care. What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.
About the Role
McKesson is a Fortune 10 healthcare company focused on improving health outcomes through technology, innovation, and operational excellence. We are seeking a highly experienced Lead - Operational Strategy & Execution to drive strategic alignment, governance, portfolio visibility, and execution discipline across large-scale technology and business initiatives. This is a highly visible individual contributor role that partners closely with executive leaders, business stakeholders, technology teams, and delivery organizations. The successful candidate will translate organizational strategy into actionable plans, operating rhythms, governance mechanisms, and performance insights that accelerate decision-making and maximize value delivery.
What You'll Do
Drive execution discipline, operational clarity and effectiveness, and strategic alignment across the Data, Analytics and AI service area. Translate business strategy into operating plans, priorities, milestones, and measurable outcomes. Drive and influence portfolio prioritization, dependency management, and resource alignment across complex workstreams. Design and optimize operating models, governance structures, decision forums, and execution cadences. Develop executive-ready narratives, presentations, QBR content, dashboards, briefings, and leadership communications. Build and monitor KPIs, financial reporting, portfolio dashboards, business impact, value realization measures, and connecting investments to outcomes. Partner with business, finance, operations, and technology leaders to identify risks, resolve blockers, and drive accountability. Prepare structured inputs, trade-offs, and insights that accelerate timely, informed decisions.
Basic Requirements
10+ years of experience in strategic program management, portfolio management, business operations, PMO leadership, strategy execution, or related disciplines. Bachelor's degree in Business, Information Technology, Computer Science, Engineering, or a related field. Demonstrated experience leading large, cross-functional enterprise programs or portfolios. Experience developing executive communications, strategic narratives, business reviews, and leadership presentations. Experience building and managing dashboards, KPIs, portfolio reporting, financial reporting, and performance metrics. Experience translating organizational strategy into execution plans, governance processes, and operating rhythms. Experience partnering with senior leaders and driving alignment across layers of an organization. Proven ability to influence stakeholders and drive outcomes across complex organizations without direct authority. Experience working in regulated or highly matrixed enterprise environments. Preferred Skills/Experience Strategic Planning: Deep experience translating organizational vision into executable strategies, roadmaps, and operating models. Executive Communication: Expertise creating concise executive briefings, QBRs, leadership presentations, and business narratives. Operating Model Thinking: Experience designing scalable processes, governance frameworks, and delivery cadences. Execution Discipline: Strong track record of driving multiple complex initiatives to successful outcomes. Performance & Portfolio Reporting: Expertise managing KPIs,