Associate Director, Outcomes Research

Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. The Associate Director will lead high-impact outcomes research for Tempus’s biopharma partners, sitting at the intersection of traditional outcomes research and cutting-edge data science. This is a high-visibility, client-facing role within the Data Business. You won’t just apply existing frameworks; you will develop and validate novel epidemiological methods to unlock the full potential of Tempus’s multimodal datasets. The ideal candidate is a scientific visionary who can translate complex, non-linear data into regulatory-grade insights that accelerate drug development and improve patient outcomes.

Research Design & Implementation : Oversee the end-to-end execution of retrospective database analyses. You will act as the primary architect for study protocols, ensuring they push the boundaries of current HEOR/RWE standards while maintaining scientific rigor. Scientific Thought Leadership : Serve as a subject matter expert for biopharma clients, advising them on "first-in-kind" study designs. You are expected to contribute to the broader scientific community through high-impact publications and presentations at conferences like ISPOR, ISPE, and ASCO. Client Strategy & Partnership: Partner with Key Account Directors and Business Development to identify opportunities where novel methodology can solve "unsolvable" client problems (e.g., rare disease characterization or complex biomarker validation). Methodological Innovation: Lead the development of novel approaches for RWE, including the use of external control arms (ECA), causal inference in high-dimensional data, and the integration of longitudinal clinical data with molecular/genomic signatures. Scientific Thought Leadership & Publication Strategy : Drive the strategy and roadmap for scientific dissemination. Lead the authoring and publication of high-impact peer-reviewed manuscripts, abstracts, and conference presentations to demonstrate methodologic rigor and support broader healthcare evidence generation. Cross-Functional Partnership : Bridge the gap between Data Science, Biostatistics, and Product teams to productize successful novel methods, ensuring they are scalable across the Tempus ecosystem. Project Management & Quality: Ensure all innovative research meets stringent regulatory and ethical standards (e.g., GEP, HIPAA), delivering high-quality results on timelines that match the pace of the biopharma industry. People Management : Manage a small team of outcomes research scientists, providing hands-on guidance on analytical projects and career development and growth.

Education: PhD (preferred), PharmD, or Masters degree in Epidemiology, Biostatistics, Health Economics, or a related quantitative field.

7+ years in HEOR/RWE, with at least 3 years in a leadership capacity.  Deep expertise in oncology is required. Methodological expertise: Proven track record of developing or implementing advanced analytical methods (e.g., target trial emulation, propensity score applications in complex cohorts, causal inference, or machine learning-augmented epidemiology) and creative problem solving. Technical Proficiency: Advanced skills in R or SAS. Experience working with "messy" real-world data (EHR, claims, and/or genomic data) is essential. The "Consultant" Mindset: Exceptional ability to walk into a room of biopharma executives and simplify complex methodological hurdles into a clear strategic roadmap. Leadership: Demonstrated experience managing junior