Staff Systems Support Engineer

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Staff Systems Support Engineer Cambridge - Onsite As a Staff Systems Support Engineer , you will join our Global Lab Management team and play a critical role in supporting the development of next-generation sequencing technologies. Working at the intersection of hardware, software, engineering, and science, you will help ensure our sequencing instrument fleet operates at the highest standards, empowering R&D teams to deliver the innovations that shape the future of genomics. Why Illumina? At Illumina, you'll work alongside experts across disciplines, contribute to meaningful and innovative projects, and continuously grow through new challenges and experiences. Our culture is built on collaboration, curiosity, and a shared commitment to making an impact. This is an opportunity to: Support cutting-edge sequencing technologies at the forefront of genomics innovation. Partner with world-class Chemistry, Software, Consumables, Engineering, and Integration teams. Solve complex technical challenges that directly enable scientific breakthroughs. Work in a collaborative, international environment where every contribution matters. Build your expertise while helping advance technologies that improve human health.

As a Staff Systems Support Engineer, you will work closely with Illumina's R&D teams to ensure the sequencing instrument fleet is operational, reliable, and capable of supporting critical development activities. You will leverage your technical expertise across hardware, software, firmware, and systems troubleshooting to maximize instrument performance and enable innovation.

Troubleshoot and resolve issues on sequencing instruments to support research and development activities. Collaborate with multidisciplinary teams to ensure instruments are fit for purpose, including implementing hardware and software modifications where required. Monitor instrument performance through sequencing data analysis and execute preventative maintenance and upgrade activities. Partner with EERD and Systems Integration teams to maintain fleet availability and operational excellence. Support, mentor, and provide technical guidance to junior team members. Develop and communicate key performance metrics, including failure analysis and Pareto reporting. Provide timely, clear communication to users regarding investigations, corrective actions, and repair timelines. Collaborate with global instrument and software development teams, including colleagues in the United States, to support software, firmware, and hardware upgrades. Represent the engineering support function on project teams requiring sequencing instrument expertise.

Required Qualifications & Experience Bachelor's or Master's degree in Computer Science, Engineering, Bioinformatics, Physical Sciences, or a related discipline. Significant experience supporting complex opto-electronic systems in a commercial or R&D environment. Strong troubleshooting capability across integrated hardware, firmware, and software systems. Coding experience and hands-on experience working with Linux operating systems. Experience troubleshooting and diagnosing PCB-level issues. Strong communication skills with the ability to convey technical concepts to both technical and non-technical audiences.