Senior Manager, Contracts & Pricing Strategy – KRYSTEXXA (Remote)

Career Category Value and Access Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Senior Manager Contracts & Pricing Strategy – KRYSTEXXA Live What you will do Let’s do this. Let’s change the world. The Senior Manager, Contracts & Pricing – KRYSTEXXA is a key member of the U.S. Value & Access organization responsible for analyzing market trends, pricing scenarios, and contracting impacts to help drive informed commercial decisions and forecasts. This role partners closely with Brand Marketing leadership, Finance, Accounting, Legal, Government Affairs, Trade & Distribution, Commercial Data and Analytics, Contracting and Pricing Execution, Patient Access, and Value Access Insights. The ideal candidate brings a strong understanding of the U.S. healthcare system, strong analytical skills, and attention-to-detail, with the ability to translate complex data into clear recommendations that enhance profitability, access, and business performance. Key Job Responsibilities Develop and apply financial models to assess contract structures, rebate strategies, gross-to-net (GTN) management, average sales price (ASP) impact, and access trade-offs while supporting gross-to-net forecasting across both provider and payer segments Lead the Latest Estimate Discount Rate (LEDR) modeling process by developing discount rate assumptions, evaluating pricing and contracting scenarios, impact on ASP and GTN, and aligning cross-functional stakeholders on contracting decisions and long-range planning Partner closely with the Coverage Lead to develop and execute contracting strategies across payer and provider segments Collaborate with Finance to incorporate contracting and pricing strategy insights into Quarterly Business Reviews, Long-Range Scenario (LRS) planning and other forecasting exercises Partner with Market Access, Site of Infusion Account Management, Finance, Legal, Government Pricing, and Commercial teams to align contracting strategies with business objectives and compliance requirements Support future launches (i.e., KRYSTEXXA Sub-Q and competitive launches) through competitive