Sr. Manager, Biostatistician / Programmer

Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life-threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy through a portfolio of innovative technologies, including autologous, allogeneic, and in vivo cell therapy approaches. Our research spans chimeric antigen receptor T-cell (CAR-T), T-cell receptor (TCR-T), natural killer (NK) cell-based therapies, and other emerging platforms designed to transform the treatment of serious diseases. From our global network of research and development sites, we are committed to discovering and developing safe, effective, and cutting-edge therapies for patients worldwide.

Legend Biotech entered into a global collaboration agreement with Johnson & Johnson to jointly develop and commercialize CARVYKTI® (ciltacabtagene autoleucel; cilta-cel). Through this strategic partnership, we combine complementary expertise and capabilities to advance innovative immunotherapies for patients living with multiple myeloma.

Legend Biotech is seeking a Sr. Manager, Biostatistician/Programmer as part of the Clinical team based in Somerset, NJ.

The Sr. Manager, Biostatistician/Programmer plays a critical hands-on role in supporting Legend Biotech’s clinical development programs by transforming clinical trial data into high-quality analyses, tables, figures, and listings that inform decision-making. This role partners closely with clinical, translational, research stakeholders to deliver timely insights, conduct exploratory and ad hoc analyses, and deeply understand the medical and scientific questions underlying the data. The position requires strong programming expertise, data agility, intellectual curiosity, and the ability to work independently in a fast-moving biotech environment.

• Develop, validate, and maintain high-quality Tables, Figures, and Listings (TFLs) to support ongoing clinical trials, interim analyses, and internal/external deliverables in compliance with study requirements and standards.

• Perform hands-on statistical programming and data manipulation to support planned and ad hoc analyses, addressing evolving clinical and scientific questions.

• Independently explore and interrogate clinical trial data to identify trends, anomalies, and insights that support clinical interpretation and decision-making.

• Collaborate closely with Biostatistics, Clinical Development, Clinical Operations, Data Management,

• Translational research and Medical teams to ensure