Global ERP Operations Lead, SAP Platform
Amgen
- Location
- United States - Remote
- Work model
- Remote
- Level
- Senior
- H-1B history
- 137 approvals (FY2023)
- Posted
- Sep 4, 2026
Skills
About this role
Career Category Information Systems Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Global ERP Operations Lead, SAP Platform What you will do Let’s do this. Let’s change the world. As Global ERP Operations Lead, you are responsible for the stability, performance and continuous improvement of Amgen’s ERP (SAP) platform. You lead global ERP run operations and ensure that the systems supporting critical business processes operate reliably, securely and compliantly. You combine deep SAP operational expertise with strong leadership and stakeholder management skills to ensure service excellence and drive continuous improvement across the ERP landscape.
Key Responsibilities
Lead global ERP run operations for SAP S/4HANA and integrated platforms, ensuring high availability and performance. Drive operational excellence through effective monitoring, incident, problem and change management. Establish AI-enabled ERP operations and AIOps capabilities that use operational data and telemetry to improve system resilience, accelerate issue resolution, and optimize operating costs. Define and manage operational KPIs and SLAs to ensure reliable ERP service delivery. Ensure ERP platforms meet cybersecurity, GxP, SOX and GDPR compliance requirements. Strengthen access management, segregation of duties and security patching processes. Identify opportunities for automation, standardization and modernization across ERP operations. Use operational metrics and insights to improve system resilience, user experience and cost efficiency. Lead and develop a global team of internal and partner resources. Partner closely with Solution Leads, Delivery teams and Infrastructure teams to ensure seamless system lifecycle management. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The professional we seek is an individual with these qualifications.
Basic Qualifications
Doctorate degree and 2 years of relevant experience OR Master’s degree and 4 years of experience OR Bachelor’s degree and 6 years of experience OR Associate’s degree and 10 years of experience OR High school diploma / GED and 12 years of experience Preferred Qualifications: Roughly 10 years of experience in enterprises and/or consultancy firms. Proven success leading ERP implementation and/or operations in large, global organizations, ensuring system reliability and operational excellence. Deep expertise in SAP S/4HANA, SAP BTP and RISE with SAP/non-SAP environments. Strong experience managing complex system integrations and enterprise-scale SAP landscapes. Demonstrated ability to lead service delivery and vendor management through KPIs, SLAs and continuous improvement. Experience implementing automation and operational optimization initiatives within ERP platforms. Solid understanding of cloud infrastructure (AWS) and enterprise service management