Senior Scientist, Biologics Design and Function
Johnson & Johnson
- Location
- Spring House, Pennsylvania, United States of America
- Work model
- On-Site
- Level
- Senior
- H-1B history
- 2 approvals (FY2023)
- Posted
- Aug 26, 2026
Skills
About this role
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com . As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit. Job Function: Discovery & Pre-Clinical/Clinical Development Job Sub Function: Biotherapeutics R&D Job Category: Scientific/Technology All Job Posting Locations: Spring House, Pennsylvania, United States of America Job Description: About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine We are searching for the best talent for a Senior Scientist, Biologics Design and Function to be located in Spring House, PA. Purpose: The Biologics Design & Function team within Biologics Discovery is responsible for translating biological insights into differentiated therapeutic strategies and functional outcomes across biologic modalities. We address complex scientific questions and solve novel challenges with creativity, calculated risk taking, and a multi-disciplinary, collaborative spirit. We are seeking a highly motivated Senior Scientist to help define, evaluate, and advance innovative therapeutic concepts that use the immune system to treat disease. This individual will combine deep expertise in immune cell biology with hands-on laboratory experience to investigate therapeutic mechanisms of action, establish functional differentiation, and evaluate molecule optimization across a diverse discovery portfolio. This role requires scientific curiosity, strong problem-solving skills, and a passion for addressing complex biological questions. The successful candidate will collaborate closely with protein engineers, computational scientists, drug discovery teams, and therapeutic area scientists to generate mechanistic insights that drive therapeutic innovation. The position provides the opportunity to contribute directly to discovery programs while developing scientific leadership capabilities through participation on multidisciplinary project teams and strategic discovery initiatives. You will be responsible for: Designing, implementing, and interpreting mechanistic and functional studies that guide molecule design, establish therapeutic differentiation, and inform program decisions. Serving as subject matter expert to apply immunological and biological insights to guide molecule optimization and inform key discovery-stage decisions. Developing and implementing innovative assays, experimental approaches, and technologies that enhance understanding of therapeutic mechanisms and biological function. Evaluating emerging technologies and developing innovative approaches to accelerate biologics functional assay workflows and therapeutic discovery. Demonstrating abilities to solve complex biological problems and translate mechanistic insights into actionable therapeutic strategies. Independently communicating scientific findings through presentations, technical reports, patent applications, publications, and