Scientist – Molecular Analytics (1 Year Contract)

Career Category Scientific Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Scientist – Molecular Analytics Reports to: Principal Scientist Location: Burnaby, British Columbia (Onsite) Type: 1 year contract, possibility of extension What you will do: Let’s do this. Let’s change the world. In this vital role you will join the Biologics Engineering with Advanced Mass Spectrometry (BEAM) team at our Research facility in Burnaby, BC, Canada. We are looking for a highly motivated scientist to work with cross functional teams to characterize both reagent and therapeutic protein candidates using various analytical techniques to support Amgen’s early phase discovery programs. The successful candidate will work in a highly collaborative team environment and contribute independently to diverse functions depending upon project needs and priority. Maintain and oversee mass spectrometry and liquid chromatography instrumentation and laboratory processes Perform intact and sub-unit protein mass analysis to confirm protein identity supporting a variety of large molecules Perform peptide analysis to confirm sequence and protein modifications Train protein biochemistry staff on sample preparation and sample submission and assist/troubleshoot with instrumentation, software and data interpretation Participate in the design, development, implementation, method transfer and qualification of novel LC-MS and LC-MS/MS methods Analyze and interpret data using automated workflows and maintain file organization What we expect of you We are all different, yet we all use our unique contributions to serve patients. The scientific professional we seek is a person with these qualifications Basic Qualifications: Bachelor’s Degree in Chemistry, Biochemistry, Molecular and Cellular Biology or a related discipline and 5 years of scientific laboratory experience. OR Master’s Degree in a closely related scientific discipline and 2+ years of laboratory experience OR PhD and Mass Spectrometry and Chromatography experience Preferred Qualifications: Training in analytical chemistry/biochemistry, including proficiency in operation of QTOF and Orbitrap mass spectrometers and UPLC instrumentation with 5+ years general laboratory experience. Prior experience supporting users is highly desired 2+ years of hands-on experience in protein analytics. Experience with intact, sub-unit protein mass and peptide analysis is preferred Familiarity with common LC-MS data acquisition and analysis software such as MassHunter, Byos, Proteome Discoverer, MASCOT, Xcalibur, etc. is desired Experience with handling and analyzing large datasets is an asset Ability to follow established laboratory protocols and adhere to data standards; attention to detail and careful execution of laboratory tasks are essential Strong oral and written communication skills and organizational skills