Senior Scientist, Modeler

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com . As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit. Job Function: Discovery & Pre-Clinical/Clinical Development Job Sub Function: Biotherapeutics R&D Job Category: Scientific/Technology All Job Posting Locations: Malvern, Pennsylvania, United States of America, Spring House, Pennsylvania, United States of America Job Description: About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine We are searching for the best talent for Senior Scientist, Modeler, to join our team in Malvern or Spring House, PA. Purpose: In this role, you will serve as an individual contributor with expertise in applied modeling for Cell and Gene Therapy process and product development. The role will build fit-for-purpose models to support a broad range of data consumption use cases, including time series modeling, process characterization, optimization, scale translation, data interpretation, and decision-making across development teams. In addition, this role will require innate familiarity with the foundational requirement needed to support end-to-end Digital Twins by scalable modeling components that connect process/analytical knowledge, experimental data, mechanistic and statistical models, and user-facing tools. The successful candidate will collaborate closely with scientists, engineers, data and automation partners, Digital Twin leads, and project teams to identify high-value modeling use cases, translate scientific questions into model-based workflows, and deliver interpretable outputs that support Cell and Gene Therapy development strategies. You will be responsible for: Build and deploy fit-for-purpose models that support routine Cell and Gene Therapy development activities, including time series modeling, process characterization, optimization, scale-up/scale-down translation, comparability assessments, and data-driven troubleshooting. Develop mechanistic, statistical, hybrid, and/or machine learning models that translate complex development data into actionable insights for scientists, engineers, and project teams. Create user-accessible modeling solutions, dashboards, workflows, or decision-support tools that enable project teams to apply model outputs in day-to-day development decisions. Partner with scientists, engineers, data scientists, automation experts, IT architects, and Digital Twin leads to define data requirements, model inputs, and reusable data structures needed to support modeling workflows and broader data science initiatives. Contribute modeling components that support development of end-to-end Cell and Gene Therapy Digital Twins, including unit operation models, model-ready data structures, simulation workflows, and integration-ready outputs. Support model verification, validation, documentation, lifecycle management, and appropriate governance to ensure models are reliable,