Senior Director, IT - G&A

MISSION

Mirum Pharmaceuticals is a biopharmaceutical company dedicated to transforming the treatment of rare diseases. We are passionate about advancing scientific discoveries to become important medicines for rare disease patients. We are collaborative, creative, and experienced professionals and we’re looking to augment our team with other individuals who embody our values: care, be real, get it done, and have fun, seriously.

Lead the technology strategy, delivery, and operational support for Mirum's General & Administrative functions, including Finance, Accounting, Human Resources, and Legal. This role will serve as the senior IT business partner and single point of accountability for enterprise applications, ensuring that technology investments support scalable operations, effective controls, reliable data, and excellent employee experience.

The ideal candidate brings a strong blend of life sciences business knowledge, enterprise applications expertise, financial and compliance acumen, and people leadership. This leader will own the G&A technology roadmap end-to-end, chair the G&A Functional IT Governance Committee, and lead a team of employees, consultants, vendors, and managed-service partners.

JOB FUNCTIONS/RESPONSIBILITIES

Strategic Leadership & Business Partnership

• Serve as the IT thought partner to Finance, Accounting, Human Resources, Legal, and other corporate-function leaders.

• Develop and execute a multi-year G&A technology roadmap aligned with business priorities, company growth, risk management, and compliance requirements. This roadmap represents a $3.5–4.0M investment over 24 months across six workstreams, currently in execution

• Act as the front door for G&A technology demand, translating business priorities into clear capabilities, investment proposals, and delivery plans.

• Chair the G&A Functional IT Governance Committee, facilitating prioritization, approvals, trade-off decisions, and escalation of cross-functional, budget, or compliance matters.

Application Portfolio & Program Delivery

• Own the lifecycle, roadmap, integration, enhancement, and support of business-critical G&A platforms, including ERP and financial systems, planning and reporting tools, HR and payroll systems, legal and corporate applications, and related integrations.

• Lead complex cross-functional initiatives such as finance process automation, systems integration, master-data improvements, reporting modernization, and budget-versus-actuals reconciliation.

• Ensure prioritized projects are delivered on time, within scope, within budget, and with measurable business outcomes using established IT governance and project delivery practices.

• Define business requirements, process designs, data definitions, testing strategies, and business acceptance criteria in partnership with functional stakeholders.

• Own change management, training, communications, and adoption planning for new and enhanced solutions.

Financial Controls, Compliance & Risk Management

• Ensure SOX-relevant systems and processes maintain appropriate application controls, access controls, segregation of duties, change controls, and audit evidence.

• Partner with Finance, Internal Audit, Legal, Privacy, Security, and external auditors to assess risks, remediate control gaps, and support audits and compliance reviews.

• Ensure G&A applications comply with applicable data privacy, records-management, cybersecurity, and corporate policy requirements.

• Maintain clear system ownership, support models,