Senior Principal SRE Engineering

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.  About the technology organization Technology at Lilly builds and operates mission-critical digital products and platforms that support the discovery, development, and delivery of medicines that make life better for people around the world. Our teams operate in highly regulated, high-availability environments, where operational excellence, reliability, and quality are non-negotiable. Within Tech@Lilly, the Digital Core organization applies a product, platform, and reliability-first mindset, ensuring that operational capabilities scale sustainably across the enterprise.

Tech@Lilly builds and maintains capabilities using pioneering technologies like the most prominent tech companies. What differentiates Lilly IT is that we redefine what's possible through tech to advance our purpose, creating medicines that make life better for people around the world, including data-driven drug discovery, connected clinical trials, resilient enterprise platforms, and intelligent digital operations. We hire the best technology professionals from a variety of backgrounds, so they can bring an assortment of knowledge, skills, and diverse thinking to deliver creative solutions in every area of our business. The Digital Core team leads Lilly's transformation into the Digital and AI era. They inspire digitally empowered teams to new ways of working and accelerate innovation and agility. This team powers and advances the entire company by building and maintaining world-class technology capabilities and platforms. Lilly Capability Centre India (LCCI), Hyderabad, is Lilly's premier Global Technology Hub, harnessing data, AI, analytics, and digital solutions to revolutionize healthcare and improve patient outcomes worldwide. The Reliability Engineering team is the engineering-first function that owns the stability, observability, and operational quality of a multi-application production estate. It operates in close partnership with the engineering team that builds the agentic automation platform, and is in active transition from human-executed operations to engineering-led, agent-assisted reliability. Role summary As the Senior Principal SRE Engineering Lead, you are the senior-most engineering authority for the reliability of the supported production estate. You own the bar for what reliable means in this organization: service-level objectives, error-budget governance, observability standards, and the engineering practices that protect both production and the team's engineering time. This role is the judgment layer between an agent's recommendation and a production change. You combine engineering rigor with operational pragmatism, and you decide which patterns surfaced from production warrant durable engineering investment. You hold the SRE engineering bar within the function — the cross-pillar reference architecture is owned by the Senior Architect, but the practice, standards, and engineering judgment of reliability at this site are yours. You are a senior individual contributor. You do not manage people. You partner with the Reliability Leader, the Senior Principal Tech Shift Lead in the same pillar, the Senior Architect, and the senior engineering principals in the agentic automation team. Success is measured by organizational impact, sustained reliability outcomes, and the ability