Sr. Director, Cloud and Infrastructure Transformation
Pfizer
- Location
- United States - New York - New York City
- Work model
- On-Site
- Level
- Staff
- H-1B history
- 9 approvals (FY2023)
- Posted
- Aug 23, 2026
About this role
Use Your Power for Purpose At the heart of Pfizer's Digital transformation sits Infrastructure & Cloud, enabling modern cloud platforms and engineering capabilities that accelerate scientific discovery, empower researchers, and improve patient outcomes worldwide. Pfizer is seeking a highly accomplished technology leader who combines enterprise-scale strategic thinking with deep technical expertise in cloud, infrastructure, networking, and platform engineering. This role will shape the future of Pfizer's cloud and infrastructure ecosystem, enabling AI/ML-powered research, advanced analytics, and next-generation digital capabilities that support breakthrough science and drug discovery. The successful candidate will be equally comfortable discussing business strategy with executive leadership, guiding large-scale transformation initiatives, and engaging directly with architects and engineers on critical technical decisions. This is a leadership role for someone who has not only led transformation programs but has personally helped design, build, and scale modern cloud platforms and infrastructure capabilities. At Pfizer, your work will directly contribute to the technologies that enable scientists to accelerate research, unlock insights from complex data, and develop innovative medicines for patients around the world. Pfizer seeks individuals who are highly self-motivated, intellectually curious, collaborative, and committed to continuous learning and growth. What You Will Achieve The Senior Director, Cloud & Infrastructure Transformation serves as both a strategic technology executive and a technical thought leader for Pfizer's cloud and infrastructure landscape. This leader will define future-state infrastructure strategy while ensuring the successful execution of complex, enterprise-scale initiatives spanning cloud, networking, data center modernization, platform engineering, and AI infrastructure. You will lead a team of senior leaders, architects, and engineering organizations while helping establish the technology vision, engineering standards, and operating models required to support Pfizer's digital future. You will be expected to drive business outcomes through technology strategy while maintaining the technical depth and credibility necessary to guide architecture decisions, challenge assumptions, and ensure engineering excellence.
Key Responsibilities
Define and execute Pfizer's multi-year cloud and infrastructure transformation strategy, aligning technology investments with business and scientific priorities. Lead enterprise-wide modernization initiatives spanning multi-cloud environments, AI/ML platforms, network transformation, infrastructure automation, and data center evolution. Serve as a senior technical authority, providing guidance on architecture, platform engineering, cloud operations, resiliency, security, and infrastructure modernization. Partner with architects and engineering leaders to evaluate and influence critical technology decisions, ensuring scalable, secure, and operationally resilient solutions. Drive adoption of cloud-native architectures, Infrastructure as Code, automation, observability, DevOps, and Site Reliability Engineering practices. Establish technology roadmaps and engineering standards that support innovation, operational excellence, and regulatory compliance. Build strong partnerships across Digital, Security, Research, and Business organizations to accelerate enterprise transformation initiatives. Lead and develop high-performing teams of Directors, Senior Managers, and technical leaders while cultivating a culture of innovation, accountability, and technical excellence. Mainly influencing to start, followed by a larger team over time. Influence senior executive stakeholders and drive alignment across a complex, global, matrixed organization. Evaluate emerging technologies and industry trends to identify opportunities that improve Pfizer's technology capabilities and