Sr. Director, Strategy - Oncology & Multispecialty

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.   What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you. This role offers location flexibility and is open to candidates across the United States. Candidates based in the Dallas–Fort Worth (DFW) area will be hired in a hybrid capacity and are expected to work onsite at our Las Colinas office a minimum of two (2) days per week, with the remaining days worked remotely. Specific in ‑ office days may be designated based on team needs and business priorities.

The Sr. Director, Strategy (Oncology & Multispecialty) is the first level of true initiative ownership, owning strategic initiatives end-to-end: framing the problem, designing the approach, leading the analytical team, developing the recommendation, and syndicating it with business leaders through to a decision. This is a senior-level individual contributor role. Initiatives span both commercial segments — provider-facing (GPO, specialty distribution, specialty pharmacy, alternate site infusion, practice management) and biopharma-facing (clinical trial site management, real-world evidence, clinicogenomic data) — and frequently sit at the intersection between the two, where the segment’s most distinctive strategic questions live. The Sr. Director leads cross-functional initiative teams and guides the work of Senior Managers, analysts, and business partners through structured problem solving, analytical direction, and high-quality feedback, while formal performance and development accountability remains with people leaders. What You’ll Do: Strategic Initiative Leadership Lead strategic initiatives end-to-end — from problem definition and workplan design through analysis, recommendation development, syndication, and hand-off to execution owners. Structure ambiguous, contested problems into clear hypotheses, workplans, and decision paths; insist on clear problem definition, logic, and evidence. Develop recommendations that reflect genuine choices with explicit trade-offs — not lists of initiatives — grounded in the financial architecture of specialty care and biopharma services markets. Prepare and run productive problem-solving sessions with business partners across both franchises; engage stakeholders in joint problem solving rather than delivering conclusions to them. Specialty Value Chain Economics & Financial Analysis Serve as a knowledgeable resource on the financial architecture of the specialty care and biopharma services value chains — including buy-and-bill economics, 340B mechanics, GPO and distribution economics, specialty pharmacy P&Ls, infusion site-of-care dynamics, and the economics of clinical research and RWE businesses among others as required by the business. Direct and quality-control the financial models built by the team; ensure every significant analysis identifies the assumptions that matter most and translates market shifts into quantified P&L implications. Analyze the financial and competitive consequences of regulatory and policy developments — 340B reform, Part B reimbursement policy, oncology care model evolution, biosimilar adoption, and FDA policy on RWE — within the scope of assigned initiatives. Contribute to scenario analysis of structural moves by value chain participants — practice consolidation, PBM vertical integration, health system expansion into community oncology, and technology platform entry among others. Thought Partnership & Syndication Act